Australian Aridol Calculator

PD₁₅ Calculator for ARIDOL^® (mannitol powder for inhalation) Bronchial Challenge Test Kit

Important:

Please see full prescribing information (which can be found on this website) before prescribing this test.

Aridol is indicated for identifying bronchial hyperresponsiveness to assist in the diagnosis of Asthma [TGA approved Aridol Product Information]

Information entered into the Aridol Calculator is not stored online or transmitted to any third party including Pharmaxis. For further information contact Pharmaxis Medical Information at med.info@pharmaxis.com.au.

MANNITOL BRONCHIAL CHALLENGE TEST

Test Date:

PATIENT DETAILS

*Given Name:

Middle Initial:

*Family Name:

Weight (kg):

Height (cm):

Age (years):

Gender:

*mandatory fields

FVC (L):

*Pre-challenge FEV₁ (L):

FEV₁/FVC:

FEF_25-75 (L/s):

PEFR:

% predicted:

Notes:

The ARIDOL inhalation test should be conducted only under the supervision of a physician or other appropriate trained personnel thoroughly familiar with all aspects of bronchial provocation tests and management of acute bronchospasm.

General precautions when conducting spirometry and bronchial provocation testing should be observed if FEV₁<1.5 litres or <70% of the predicted values.

Enter the "best of two" FEV₁ values for each Aridol dose in the fields below and press the return or enter key. Refreshing your browser window will clear the form.

Dose (mg)	Total dose (mg)	FEV₁ (litre)	Change from last dose (%)	Change from 0 mg (%)
0	0
5	5
10	15
20	35
40	75
80	155
160	315
160	475
160	635

Change in FEV₁

CALCULATED RESULTS

A positive result is defined as a ≥ 15% fall in FEV₁ from the FEV₁ at 0 mg dose or ≥ 10% fall in FEV₁ between consecutive doses.

The PD₁₅ — provocative dose to cause a 15% fall in FEV₁ — will be calculated and displayed if a ≥ 15% fall in FEV₁ occurs.

The RDR — Response / Dose ratio — will be calculated if a positive result occurs.

Dose prior to ≥ 15% fall in FEV₁ (mg):

Total dose at positive result (mg):

PD₁₅ dose (mg):

Fall in FEV₁ prior to ≥ 15% fall (%):

Actual fall at positive result (%):

Response / Dose ratio:

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PD₁₅ Calculator by Intraversed®

PD15 Calculator for ARIDOL® (mannitol powder for inhalation) Bronchial Challenge Test Kit

Important:

Dose (mg)

Total dose (mg)

FEV1 (litre)

Change from last dose (%)

Change from 0 mg (%)

Change in FEV1

PD₁₅ Calculator for ARIDOL^® (mannitol powder for inhalation) Bronchial Challenge Test Kit

FEV₁ (litre)

Change in FEV₁